# American Institute of Mathematical Sciences

September  2016, 5(3): 399-430. doi: 10.3934/eect.2016011

## The shape derivative for an optimization problem in lithotripsy

 1 Alpen-Adria-Universität Klagenfurt, Universitätsstraße 65-67, 9020 Klagenfurt 2 University of Graz, Heinrichstraße 36, 8010 Graz, Austria

Received  January 2016 Revised  March 2016 Published  August 2016

In this paper we consider a shape optimization problem motivated by the use of high intensity focused ultrasound in lithotripsy. This leads to the problem of designing a Neumann boudary part in the context of the Westervelt equation, which is a common model in nonlinear acoustics. Based on regularity results for solutions of this equation and its linearization, we rigorously compute the shape derivative for this problem, relying on the variational framework from [9].
Citation: Barbara Kaltenbacher, Gunther Peichl. The shape derivative for an optimization problem in lithotripsy. Evolution Equations & Control Theory, 2016, 5 (3) : 399-430. doi: 10.3934/eect.2016011
##### References:
 [1] R. A. Adams and J. J. F. Fournier, Sobolev Spaces,, Pure and Applied Mathematics. Elsevier Science, (2003). Google Scholar [2] K. Atkinson and W. Han, Theoretical Numerical Analysis,, Number 39 in Texts in Applied Mathematics. Springer, (2009). doi: 10.1007/978-1-4419-0458-4. Google Scholar [3] A. Ben Abda, F. Bouchon, G. Peichl, M. Sayeh and R. Touzani, A Dirichlet-Neumann cost functional approach for the Bernoulli problem,, Journal of Engineering Mathematics, 81 (2013), 157. doi: 10.1007/s10665-012-9608-3. Google Scholar [4] C. Clason and B. Kaltenbacher, Avoiding degeneracy in the Westervelt equation by state constrained optimal control,, Evolution Equations and Control Theory, 2 (2013), 281. doi: 10.3934/eect.2013.2.281. Google Scholar [5] C. Clason, B. Kaltenbacher and S. Veljović, Boundary optimal control of the Westervelt and the Kuznetsov equation,, Journal of Mathematical Analysis and Applications, 356 (2009), 738. doi: 10.1016/j.jmaa.2009.03.043. Google Scholar [6] C. Delfour and J. P. Zolésio, Shapes and Geometries: Metrics, Analysis, Differential Calculus, and Optimization, Second Edition,, Advances in Design and Control. Society for Industrial and Applied Mathematics (SIAM, (3600). doi: 10.1137/1.9780898719826. Google Scholar [7] L. C. Evans, Partial Differential Equations, volume 19 of Graduate Studies in Mathematics,, American Mathematical Society, (1998). Google Scholar [8] P. Grisvard, Elliptic Problems in Nonsmooth Domains,, Pitman Advanced Pub. Program Boston, (1985). Google Scholar [9] K. Ito, K. Kunisch and G. Peichl, Variational approach to shape derivatives,, ESAIM: Control, 14 (2008), 517. doi: 10.1051/cocv:2008002. Google Scholar [10] V. Nikolić and B. Kaltenbacher, Sensitivity analysis for an optimal shape of a focusing lens in lithotripsy,, Applied Mathematics and Optimization, (2016), 1. Google Scholar [11] I. Shevchenko and B. Kaltenbacher, Absorbing boundary conditions for nonlinear acoustics: The Westervelt equation,, J. Comp. Phys., 302 (2015), 200. doi: 10.1016/j.jcp.2015.08.051. Google Scholar [12] J. Sokolowski and J. P. Zolesio, Introduction to Shape Optimization: Shape Sensitivity Analysis,, Springer Series in Computational Mathematics, (1992). doi: 10.1007/978-3-642-58106-9. Google Scholar

show all references

##### References:
 [1] R. A. Adams and J. J. F. Fournier, Sobolev Spaces,, Pure and Applied Mathematics. Elsevier Science, (2003). Google Scholar [2] K. Atkinson and W. Han, Theoretical Numerical Analysis,, Number 39 in Texts in Applied Mathematics. Springer, (2009). doi: 10.1007/978-1-4419-0458-4. Google Scholar [3] A. Ben Abda, F. Bouchon, G. Peichl, M. Sayeh and R. Touzani, A Dirichlet-Neumann cost functional approach for the Bernoulli problem,, Journal of Engineering Mathematics, 81 (2013), 157. doi: 10.1007/s10665-012-9608-3. Google Scholar [4] C. Clason and B. Kaltenbacher, Avoiding degeneracy in the Westervelt equation by state constrained optimal control,, Evolution Equations and Control Theory, 2 (2013), 281. doi: 10.3934/eect.2013.2.281. Google Scholar [5] C. Clason, B. Kaltenbacher and S. Veljović, Boundary optimal control of the Westervelt and the Kuznetsov equation,, Journal of Mathematical Analysis and Applications, 356 (2009), 738. doi: 10.1016/j.jmaa.2009.03.043. Google Scholar [6] C. Delfour and J. P. Zolésio, Shapes and Geometries: Metrics, Analysis, Differential Calculus, and Optimization, Second Edition,, Advances in Design and Control. Society for Industrial and Applied Mathematics (SIAM, (3600). doi: 10.1137/1.9780898719826. Google Scholar [7] L. C. Evans, Partial Differential Equations, volume 19 of Graduate Studies in Mathematics,, American Mathematical Society, (1998). Google Scholar [8] P. Grisvard, Elliptic Problems in Nonsmooth Domains,, Pitman Advanced Pub. Program Boston, (1985). Google Scholar [9] K. Ito, K. Kunisch and G. Peichl, Variational approach to shape derivatives,, ESAIM: Control, 14 (2008), 517. doi: 10.1051/cocv:2008002. Google Scholar [10] V. Nikolić and B. Kaltenbacher, Sensitivity analysis for an optimal shape of a focusing lens in lithotripsy,, Applied Mathematics and Optimization, (2016), 1. Google Scholar [11] I. Shevchenko and B. Kaltenbacher, Absorbing boundary conditions for nonlinear acoustics: The Westervelt equation,, J. Comp. Phys., 302 (2015), 200. doi: 10.1016/j.jcp.2015.08.051. Google Scholar [12] J. Sokolowski and J. P. Zolesio, Introduction to Shape Optimization: Shape Sensitivity Analysis,, Springer Series in Computational Mathematics, (1992). doi: 10.1007/978-3-642-58106-9. Google Scholar
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