The effect of global travel on the spread of SARS

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2006, 3(1): 205-218. doi: 10.3934/mbe.2006.3.205

The effect of global travel on the spread of SARS

Shigui Ruan ^1, , Wendi Wang ^2, and Simon A. Levin ^3,

1.	Department of Mathematics, University of Miami, Coral Gables, FL 33124-4250, United States
2.	Department of Mathematics, Southwest Normal University, Chongqing 400715, PR, China
3.	Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, United States

Received April 2005 Revised May 2005 Published November 2005

Abstract
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The goal of this paper is to study the global spread of SARS. We propose a multiregional compartmental model using medical geography theory (central place theory) and regarding each outbreak zone (such as Hong Kong, Singapore, Toronto, and Beijing) as one region. We then study the effect of the travel of individuals (especially the infected and exposed ones) between regions on the global spread of the disease.

Keywords: epidemic model, medical geography, basic reproduction number, central place theory., global travel.

Mathematics Subject Classification: 92D3.

Citation: Shigui Ruan, Wendi Wang, Simon A. Levin. The effect of global travel on the spread of SARS. Mathematical Biosciences & Engineering, 2006, 3 (1) : 205-218. doi: 10.3934/mbe.2006.3.205

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