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In this paper, a novel spreading dynamical model for *Echinococcosis* with distributed time delays is proposed. For the model, we firstly give the basic reproduction number $\mathcal{R}_0$ and the existence of a unique endemic equilibrium when $\mathcal{R}_0>1$. Furthermore, we analyze the dynamical behaviors of the model. The results show that the dynamical properties of the model is completely determined by $\mathcal{R}_0$. That is, if $\mathcal{R}_0<1$, the disease-free equilibrium is globally asymptotically stable, and if $\mathcal{R}_0>1$, the model is permanent and the endemic equilibrium is globally asymptotically stable. According to human *Echinococcosis* cases from January 2004 to December 2011 in Xinjiang, China, we estimate the parameters of the model and study the transmission trend of the disease in Xinjiang, China. The model provides an approximate estimate of the basic reproduction number $\mathcal{R}_0=1.23$ in Xinjiang, China. From theoretic results, we further find that *Echinococcosis* is endemic in Xinjiang, China. Finally, we perform some sensitivity analysis of several model parameters and give some useful measures on controlling the transmission of *Echinococcosis*.

We study the optimal nonlinearity control problem for the nonlinear Schrödinger equation $iu_{t} = -\triangle u+V(x)u+h(t)|u|^α u$, which is originated from the Fechbach resonance management in Bose-Einstein condensates and the nonlinearity management in nonlinear optics. Based on the global well-posedness of the equation for $0<α<\frac{4}{N}$, we show the existence of the optimal control. The Fréchet differentiability of the objective functional is proved, and the first order optimality system for $N≤ 3$ is presented.

Minimize $\quad \int_a^bL(x,u(x),u'(x),u''(x))dx,\quad u\in\Omega$

with a second-order Lagrangian is considered. In absence of any smoothness or convexity condition on $L$, we present an existence theorem by means of the integro-extremal technique. We also discuss the monotonicity property of the minimizers. An application to the extended Fisher-Kolmogorov model is included.

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