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We consider a class of nonlocal generalized perimeters which includes fractional perimeters and Riesz type potentials. We prove a general isoperimetric inequality for such functionals, and we discuss some applications. In particular we prove existence of an isoperimetric profile, under suitable assumptions on the interaction kernel.

We consider volume-constrained minimizers of the fractional perimeter with the addition of a potential energy in the form of a volume integral. Such minimizers are solutions of the prescribed fractional curvature problem. We prove existence and regularity of minimizers under suitable assumptions on the potential energy, which cover the periodic case. In the small volume regime we show that minimizers are close to balls, with a quantitative estimate.

We study various regularity properties of minimizers of the $\Phi$–perimeter, where $\Phi$ is a norm. Under suitable assumptions on $\Phi$ and on the dimension of the ambient space, we prove that the boundary of a cartesian minimizer is locally a Lipschitz graph out of a closed singular set of small Hausdorff dimension. Moreover, we show the following anisotropic Bernstein-type result: any entire cartesian minimizer is the subgraph of a monotone function depending only on one variable.

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