In this paper we consider the non-stationary 1-D flow of a compressible viscous and heat-conducting micropolar fluid, assuming that it is in the thermodynamically sense perfect and polytropic. Since the strong nonlinearity and degeneracies of the equations due to the temperature equation and vanishing of density, there are a few results about global existence of classical solution to this model. In the paper, we obtain a global classical solution to the equations with large initial data and vacuum. Moreover, we get the uniqueness of the solution to this system without vacuum. The analysis is based on the assumption $ \kappa(\theta) = O(1+\theta^q) $ where $ q\geq0 $ and delicate energy estimates.
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