We study Cauchy problem of a class of viscous Camassa-Holm equations (or Lagrangian averaged Navier-Stokes equations) with fractional diffusion in both smooth bounded domains and in the whole space in two and three dimensions. Order of the fractional diffusion is assumed to be $ 2s $ with $ s\in [n/4,1) $, which seems to be sharp for the validity of the main results of the paper; here $ n = 2,3 $ is the dimension of space. We prove global well-posedness in $ C_{[0,+\infty)}(D(A))\cap L^2_{[0,+\infty),loc}(D(A^{1+s/2})) $ whenever the initial data $ u_0\in D(A) $, where $ A $ is the Stokes operator. We also prove that such global solutions gain regularity instantaneously after the initial time. A bound on a higher-order spatial norm is also obtained.
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