# American Institute of Mathematical Sciences

August  2004, 4(3): 595-605. doi: 10.3934/dcdsb.2004.4.595

## Impulsive vaccination of sir epidemic models with nonlinear incidence rates

 1 Department of Information and Computation Sciences, Guangxi Institute of Technology, Liuzhou 545006, China 2 Institute of Mathematics, Academy of Mathematics and System Sciences, Academia Sinia, Beijing 100080, China

Received  December 2002 Revised  March 2004 Published  May 2004

The impulsive vaccination strategies of the epidemic SIR models with nonlinear incidence rates $\beta I^{p}S^{q}$ are considered in this paper. Using the discrete dynamical system determined by the stroboscopic map, we obtain the exact periodic infection-free solution of the impulsive epidemic system and prove that the periodic infection-free solution is globally asymptotically stable. In order to apply vaccination pulses frequently enough so as to eradicate the disease, the threshold for the period of pulsing, i.e. $\tau _{max}$ is shown, further, by bifurcation theory, we obtain a supercritical bifurcation at this threshold, i.e. when $\tau>\tau_{max}$ and is closing to $\tau_{max}$, there is a stable positive periodic solution. Throughout the paper, we find impulsive epidemiological models with nonlinear incidence rates $\beta I^{p}S^{q}$ show a much wider range of dynamical behaviors than do those with bilinear incidence rate $\beta SI$ and our paper extends the previous results, at the same time, theoretical results show that pulse vaccination strategy is distinguished from the conventional strategies in leading to disease eradication at relatively low values of vaccination, therefore impulsive vaccination strategy provides a more natural, more effective vaccination strategy.
Citation: Jing Hui, Lansun Chen. Impulsive vaccination of sir epidemic models with nonlinear incidence rates. Discrete and Continuous Dynamical Systems - B, 2004, 4 (3) : 595-605. doi: 10.3934/dcdsb.2004.4.595
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