American Institute of Mathematical Sciences

Advanced
  • Previous Article
    Some remarks on a singular reaction-diffusion system arising in predator-prey modeling
  • DCDS-B Home
  • This Issue
  • Next Article
    Fast reaction limit and long time behavior for a competition-diffusion system with Dirichlet boundary conditions
July  2007, 8(1): 45-60. doi: 10.3934/dcdsb.2007.8.45

An age and spatially structured model of tumor invasion with haptotaxis

Janet Dyson 1, , Eva Sánchez 2, , Rosanna Villella-Bressan 3, and  Glenn F. Webb 4,

1. 

Department of Mathematics, Mansfield College, Oxford University, Oxford, England
2. 

Depto. de Matemática Aplicada, E.T.S.I. Industriales, c. José Gutiérrez Abascal, 2, 28006 Madrid
3. 

Dipartimento di Matematica Pura e Applicata, Universita' di Padova, Padua
4. 

Mathematics Department, Vanderbilt University, Nashville, TN 37240, United States

Received  November 2006 Revised  December 2006 Published  April 2007

A model of tumor growth into surrounding tissue is analyzed. The model consists of a system of nonlinear partial differential equations for the populations of tumor cells, extracellular matrix macromolecules, oxygen concentration, and extracellular matrix degradative enzyme concentration. The spatial growth of the tumor involves the directed movement of tumor cells toward the extracellular matrix through haptotaxis. Cell age is used to track progression of cells through the cell cycle. The existence of unique global solutions is proved using the theory of fractional powers of analytic semigroup generators.
Keywords: haptotaxis, tumor model., Semigroups of operators, diffusion.
Mathematics Subject Classification: Primary:92B05,92D25,47D03,47H20; Secondary: 35M1.
Citation: Janet Dyson, Eva Sánchez, Rosanna Villella-Bressan, Glenn F. Webb. An age and spatially structured model of tumor invasion with haptotaxis. Discrete & Continuous Dynamical Systems - B, 2007, 8 (1) : 45-60. doi: 10.3934/dcdsb.2007.8.45
[1]

Chunhua Jin. Boundedness and global solvability to a chemotaxis-haptotaxis model with slow and fast diffusion. Discrete & Continuous Dynamical Systems - B, 2018, 23 (4) : 1675-1688. doi: 10.3934/dcdsb.2018069
[2]

Jiashan Zheng. Boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2017, 37 (1) : 627-643. doi: 10.3934/dcds.2017026
[3]

Sebastián Ferrer, Francisco Crespo. Parametric quartic Hamiltonian model. A unified treatment of classic integrable systems. Journal of Geometric Mechanics, 2014, 6 (4) : 479-502. doi: 10.3934/jgm.2014.6.479
[4]

Ghendrih Philippe, Hauray Maxime, Anne Nouri. Derivation of a gyrokinetic model. Existence and uniqueness of specific stationary solution. Kinetic & Related Models, 2009, 2 (4) : 707-725. doi: 10.3934/krm.2009.2.707
[5]

Angela A. Albanese, Xavier Barrachina, Elisabetta M. Mangino, Alfredo Peris. Distributional chaos for strongly continuous semigroups of operators. Communications on Pure & Applied Analysis, 2013, 12 (5) : 2069-2082. doi: 10.3934/cpaa.2013.12.2069
[6]

V. Pata, Sergey Zelik. A result on the existence of global attractors for semigroups of closed operators. Communications on Pure & Applied Analysis, 2007, 6 (2) : 481-486. doi: 10.3934/cpaa.2007.6.481
[7]

Elisabeth Logak, Chao Wang. The singular limit of a haptotaxis model with bistable growth. Communications on Pure & Applied Analysis, 2012, 11 (1) : 209-228. doi: 10.3934/cpaa.2012.11.209
[8]

Pan Zheng, Chunlai Mu, Xiaojun Song. On the boundedness and decay of solutions for a chemotaxis-haptotaxis system with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2016, 36 (3) : 1737-1757. doi: 10.3934/dcds.2016.36.1737
[9]

Niklas Kolbe, Nikolaos Sfakianakis, Christian Stinner, Christina Surulescu, Jonas Lenz. Modeling multiple taxis: Tumor invasion with phenotypic heterogeneity, haptotaxis, and unilateral interspecies repellence. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020284
[10]

Faker Ben Belgacem. Uniqueness for an ill-posed reaction-dispersion model. Application to organic pollution in stream-waters. Inverse Problems & Imaging, 2012, 6 (2) : 163-181. doi: 10.3934/ipi.2012.6.163
[11]

Amy H. Lin. A model of tumor and lymphocyte interactions. Discrete & Continuous Dynamical Systems - B, 2004, 4 (1) : 241-266. doi: 10.3934/dcdsb.2004.4.241
[12]

Elena Izquierdo-Kulich, José Manuel Nieto-Villar. Mesoscopic model for tumor growth. Mathematical Biosciences & Engineering, 2007, 4 (4) : 687-698. doi: 10.3934/mbe.2007.4.687
[13]

Bertrand Lods, Mustapha Mokhtar-Kharroubi, Mohammed Sbihi. Spectral properties of general advection operators and weighted translation semigroups. Communications on Pure & Applied Analysis, 2009, 8 (5) : 1469-1492. doi: 10.3934/cpaa.2009.8.1469
[14]

Francesco Altomare, Mirella Cappelletti Montano, Vita Leonessa. On the positive semigroups generated by Fleming-Viot type differential operators. Communications on Pure & Applied Analysis, 2019, 18 (1) : 323-340. doi: 10.3934/cpaa.2019017
[15]

Didier Bresch, Thierry Colin, Emmanuel Grenier, Benjamin Ribba, Olivier Saut. A viscoelastic model for avascular tumor growth. Conference Publications, 2009, 2009 (Special) : 101-108. doi: 10.3934/proc.2009.2009.101
[16]

Denise E. Kirschner, Alexei Tsygvintsev. On the global dynamics of a model for tumor immunotherapy. Mathematical Biosciences & Engineering, 2009, 6 (3) : 573-583. doi: 10.3934/mbe.2009.6.573
[17]

Kentarou Fujie, Akio Ito, Michael Winkler, Tomomi Yokota. Stabilization in a chemotaxis model for tumor invasion. Discrete & Continuous Dynamical Systems - A, 2016, 36 (1) : 151-169. doi: 10.3934/dcds.2016.36.151
[18]

Daniel Vasiliu, Jianjun Paul Tian. Periodic solutions of a model for tumor virotherapy. Discrete & Continuous Dynamical Systems - S, 2011, 4 (6) : 1587-1597. doi: 10.3934/dcdss.2011.4.1587
[19]

Pan Zheng. Global boundedness and decay for a multi-dimensional chemotaxis-haptotaxis system with nonlinear diffusion. Discrete & Continuous Dynamical Systems - B, 2016, 21 (6) : 2039-2056. doi: 10.3934/dcdsb.2016035
[20]

Ling Liu, Jiashan Zheng. Global existence and boundedness of solution of a parabolic-parabolic-ODE chemotaxis-haptotaxis model with (generalized) logistic source. Discrete & Continuous Dynamical Systems - B, 2019, 24 (7) : 3357-3377. doi: 10.3934/dcdsb.2018324

2019 Impact Factor: 1.27

Tools

Metrics

  • PDF downloads (42)
  • HTML views (0)
  • Cited by (19)

Other articles
by authors

[Back to Top]

Copyright © 2020 American Institute of Mathematical Sciences