American Institute of Mathematical Sciences

Advanced
September  2009, 12(2): 371-388. doi: 10.3934/dcdsb.2009.12.371

A degenerate diffusion-reaction model of an amensalistic biofilm control system: Existence and simulation of solutions

Hassan Khassehkhan 1, , Messoud A. Efendiev 2, and  Hermann J. Eberl 1,

1. 

Department of Mathematics and Statistics, University of Guelph, Guelph, On, N1G 2W1, Canada, Canada
2. 

Institute of Biomathematics and Biometry, HelmholtzZentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany

Received  September 2008 Revised  December 2008 Published  July 2009

We study a mathematical model that describes how a "good" bacterial biofilm controls the growth of a harmful pathogenic bacterial biofilm. The underlying mechanism is a modification of the local protonated acid concentration, which in turn decreases the local pH and, thus, makes growth conditions for the pathogens less favorable, while the control-agent itself is more tolerant to these changes. This system is described by a system of 5 density-dependent diffusion-reaction equations that show two nonlinear diffusion effects: porous medium degeneracy and fast diffusion. This is a multi-species expansion of a previously studied single species biofilm model. In this paper we prove the existence of solutions to this model and show in numerical simulations the effectiveness of the control mechanism.
Keywords: degeneracy, simulation., nonlinear diffusion, biofilm, probiotic.
Mathematics Subject Classification: Primary: 35K65; Secondary: 92D2.
Citation: Hassan Khassehkhan, Messoud A. Efendiev, Hermann J. Eberl. A degenerate diffusion-reaction model of an amensalistic biofilm control system: Existence and simulation of solutions. Discrete & Continuous Dynamical Systems - B, 2009, 12 (2) : 371-388. doi: 10.3934/dcdsb.2009.12.371
[1]

Blessing O. Emerenini, Stefanie Sonner, Hermann J. Eberl. Mathematical analysis of a quorum sensing induced biofilm dispersal model and numerical simulation of hollowing effects. Mathematical Biosciences & Engineering, 2017, 14 (3) : 625-653. doi: 10.3934/mbe.2017036
[2]

Nikodem J. Poplawski, Abbas Shirinifard, Maciej Swat, James A. Glazier. Simulation of single-species bacterial-biofilm growth using the Glazier-Graner-Hogeweg model and the CompuCell3D modeling environment. Mathematical Biosciences & Engineering, 2008, 5 (2) : 355-388. doi: 10.3934/mbe.2008.5.355
[3]

Gong Chen, Peter J. Olver. Numerical simulation of nonlinear dispersive quantization. Discrete & Continuous Dynamical Systems - A, 2014, 34 (3) : 991-1008. doi: 10.3934/dcds.2014.34.991
[4]

Marco Ghimenti, A. M. Micheletti. Non degeneracy for solutions of singularly perturbed nonlinear elliptic problems on symmetric Riemannian manifolds. Communications on Pure & Applied Analysis, 2013, 12 (2) : 679-693. doi: 10.3934/cpaa.2013.12.679
[5]

Jiakou Wang, Margaret J. Slattery, Meghan Henty Hoskins, Shile Liang, Cheng Dong, Qiang Du. Monte carlo simulation of heterotypic cell aggregation in nonlinear shear flow. Mathematical Biosciences & Engineering, 2006, 3 (4) : 683-696. doi: 10.3934/mbe.2006.3.683
[6]

Eleonora Messina. Numerical simulation of a SIS epidemic model based on a nonlinear Volterra integral equation. Conference Publications, 2015, 2015 (special) : 826-834. doi: 10.3934/proc.2015.0826
[7]

Walid K. Abou Salem, Xiao Liu, Catherine Sulem. Numerical simulation of resonant tunneling of fast solitons for the nonlinear Schrödinger equation. Discrete & Continuous Dynamical Systems - A, 2011, 29 (4) : 1637-1649. doi: 10.3934/dcds.2011.29.1637
[8]

Xiangrong Li, Vittorio Cristini, Qing Nie, John S. Lowengrub. Nonlinear three-dimensional simulation of solid tumor growth. Discrete & Continuous Dynamical Systems - B, 2007, 7 (3) : 581-604. doi: 10.3934/dcdsb.2007.7.581
[9]

Kolade M. Owolabi, Edson Pindza. Numerical simulation of multidimensional nonlinear fractional Ginzburg-Landau equations. Discrete & Continuous Dynamical Systems - S, 2018, 0 (0) : 835-851. doi: 10.3934/dcdss.2020048
[10]

Mauro Maggioni, James M. Murphy. Learning by active nonlinear diffusion. Foundations of Data Science, 2019, 1 (3) : 271-291. doi: 10.3934/fods.2019012
[11]

Messoud A. Efendiev, Sergey Zelik, Hermann J. Eberl. Existence and longtime behavior of a biofilm model. Communications on Pure & Applied Analysis, 2009, 8 (2) : 509-531. doi: 10.3934/cpaa.2009.8.509
[12]

Yu-Xia Wang, Wan-Tong Li. Spatial degeneracy vs functional response. Discrete & Continuous Dynamical Systems - B, 2016, 21 (8) : 2811-2837. doi: 10.3934/dcdsb.2016074
[13]

Feng Jiang, Hua Yang, Tianhai Tian. Property and numerical simulation of the Ait-Sahalia-Rho model with nonlinear growth conditions. Discrete & Continuous Dynamical Systems - B, 2017, 22 (1) : 101-113. doi: 10.3934/dcdsb.2017005
[14]

Dong Li, Xiaoyi Zhang. On a nonlocal aggregation model with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2010, 27 (1) : 301-323. doi: 10.3934/dcds.2010.27.301
[15]

Angelo Morro. Nonlinear diffusion equations in fluid mixtures. Evolution Equations & Control Theory, 2016, 5 (3) : 431-448. doi: 10.3934/eect.2016012
[16]

Brandon Lindley, Qi Wang, Tianyu Zhang. A multicomponent model for biofilm-drug interaction. Discrete & Continuous Dynamical Systems - B, 2011, 15 (2) : 417-456. doi: 10.3934/dcdsb.2011.15.417
[17]

Hermann J. Eberl, Messoud A. Efendiev, Dariusz Wrzosek, Anna Zhigun. Analysis of a degenerate biofilm model with a nutrient taxis term. Discrete & Continuous Dynamical Systems - A, 2014, 34 (1) : 99-119. doi: 10.3934/dcds.2014.34.99
[18]

Mudassar Imran, Hal L. Smith. A model of optimal dosing of antibiotic treatment in biofilm. Mathematical Biosciences & Engineering, 2014, 11 (3) : 547-571. doi: 10.3934/mbe.2014.11.547
[19]

Perla El Kettani, Danielle Hilhorst, Kai Lee. A stochastic mass conserved reaction-diffusion equation with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2018, 38 (11) : 5615-5648. doi: 10.3934/dcds.2018246
[20]

Fuzhong Cong, Yong Li. Invariant hyperbolic tori for Hamiltonian systems with degeneracy. Discrete & Continuous Dynamical Systems - A, 1997, 3 (3) : 371-382. doi: 10.3934/dcds.1997.3.371

2018 Impact Factor: 1.008

Tools

Metrics

  • PDF downloads (7)
  • HTML views (0)
  • Cited by (12)

Other articles
by authors

[Back to Top]

Copyright © 2019 American Institute of Mathematical Sciences