Firing control of ink gland motor cells in Aplysia californica

Xiangying Meng; Quanbao Ji; John Rinzel

doi:10.3934/dcdsb.2011.16.529

Article Contents

2011, Volume 16, Issue 2: 529-545. Doi: 10.3934/dcdsb.2011.16.529

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Firing control of ink gland motor cells in Aplysia californica

1.
Department of Dynamics and Control, Beihang University, Beijing 100191
2.
Mathematical and Computational Department, Anhui Huainan Normal University, Anhui, 232007
3.
Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York, NY 10012

Received: March 31, 2010

Revised: October 31, 2010

Published: August 2011

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Abstract

The release of ink in Aplysia californica occurs selectively to long-lasting stimuli. There is a good correspondence between features of the behavior and the firing pattern of the ink gland motor neurons. Indeed, the neurons do not fire for brief inputs and there is a delayed firing for long duration inputs. The biophysical mechanisms for the long delay before firing is due to a transient potassium current which activates rapidly but inactivates more slowly. Based on voltage-clamp experiments, a nine-variable Hodgkin-Huxley-like model for the ink gland motor neurons was developed by Byrne. Here, fast-slow analysis and two-parameter dynamical analysis are used to investigate the contribution of different currents and to predict various firing patterns, including the long latency before firing.

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Mathematics Subject Classification: Primary: 34C05, 34C23, 34G20; Secondary: 92C20.

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