# American Institute of Mathematical Sciences

• Previous Article
Quantitative analysis of time delays of glucose - insulin dynamics using artificial pancreas
• DCDS-B Home
• This Issue
• Next Article
Global stability of a delayed multi-group SIRS epidemic model with nonlinear incidence rates and relapse of infection
November  2015, 20(9): 3093-3114. doi: 10.3934/dcdsb.2015.20.3093

## Lyapunov functionals for virus-immune models with infinite delay

 1 Graduate School of Environmental Science, Okayama University, Okayama, 700-8530, Japan 2 Graduate School of Environmental and Life Science, Okayama University, Tsushimanaka 3-1-1, Okayama, 700-8530 3 Graduate School of Environmental and Life Science, Okayama University, Okayama, 700-8530, Japan

Received  October 2014 Revised  April 2015 Published  September 2015

We present a systematic method to construct Lyapunov functionals of delay differential equation models of infectious diseases in vivo. For generality we construct Lyapunov functionals of models with infinitely distributed delay. We begin with simpler models without delay and construct Lyapunov functionals for the complex models progressively. We construct those functionals using our result obtained previously instead of constructing each functional independently. Additionally we discuss some problems that arise from the mathematical requirements caused by the infinitely distributed delay.
Citation: Yoji Otani, Tsuyoshi Kajiwara, Toru Sasaki. Lyapunov functionals for virus-immune models with infinite delay. Discrete & Continuous Dynamical Systems - B, 2015, 20 (9) : 3093-3114. doi: 10.3934/dcdsb.2015.20.3093
##### References:

show all references

##### References:
 [1] Bao-Zhu Guo, Li-Ming Cai. A note for the global stability of a delay differential equation of hepatitis B virus infection. Mathematical Biosciences & Engineering, 2011, 8 (3) : 689-694. doi: 10.3934/mbe.2011.8.689 [2] Cuicui Jiang, Kaifa Wang, Lijuan Song. Global dynamics of a delay virus model with recruitment and saturation effects of immune responses. Mathematical Biosciences & Engineering, 2017, 14 (5&6) : 1233-1246. doi: 10.3934/mbe.2017063 [3] Yincui Yan, Wendi Wang. Global stability of a five-dimensional model with immune responses and delay. Discrete & Continuous Dynamical Systems - B, 2012, 17 (1) : 401-416. doi: 10.3934/dcdsb.2012.17.401 [4] Leonid Berezansky, Elena Braverman. Stability of linear differential equations with a distributed delay. Communications on Pure & Applied Analysis, 2011, 10 (5) : 1361-1375. doi: 10.3934/cpaa.2011.10.1361 [5] Jinliang Wang, Lijuan Guan. Global stability for a HIV-1 infection model with cell-mediated immune response and intracellular delay. Discrete & Continuous Dynamical Systems - B, 2012, 17 (1) : 297-302. doi: 10.3934/dcdsb.2012.17.297 [6] Urszula Foryś, Jan Poleszczuk. A delay-differential equation model of HIV related cancer--immune system dynamics. Mathematical Biosciences & Engineering, 2011, 8 (2) : 627-641. doi: 10.3934/mbe.2011.8.627 [7] Jinhu Xu, Yicang Zhou. Global stability of a multi-group model with vaccination age, distributed delay and random perturbation. Mathematical Biosciences & Engineering, 2015, 12 (5) : 1083-1106. doi: 10.3934/mbe.2015.12.1083 [8] Samuel Bernard, Fabien Crauste. Optimal linear stability condition for scalar differential equations with distributed delay. Discrete & Continuous Dynamical Systems - B, 2015, 20 (7) : 1855-1876. doi: 10.3934/dcdsb.2015.20.1855 [9] Samuel Bernard, Jacques Bélair, Michael C Mackey. Sufficient conditions for stability of linear differential equations with distributed delay. Discrete & Continuous Dynamical Systems - B, 2001, 1 (2) : 233-256. doi: 10.3934/dcdsb.2001.1.233 [10] Ismael Maroto, Carmen Núñez, Rafael Obaya. Exponential stability for nonautonomous functional differential equations with state-dependent delay. Discrete & Continuous Dynamical Systems - B, 2017, 22 (8) : 3167-3197. doi: 10.3934/dcdsb.2017169 [11] Tomás Caraballo, Renato Colucci, Luca Guerrini. Bifurcation scenarios in an ordinary differential equation with constant and distributed delay: A case study. Discrete & Continuous Dynamical Systems - B, 2019, 24 (6) : 2639-2655. doi: 10.3934/dcdsb.2018268 [12] Min Yu, Gang Huang, Yueping Dong, Yasuhiro Takeuchi. Complicated dynamics of tumor-immune system interaction model with distributed time delay. Discrete & Continuous Dynamical Systems - B, 2020, 25 (7) : 2391-2406. doi: 10.3934/dcdsb.2020015 [13] Lianwen Wang, Zhijun Liu, Yong Li, Dashun Xu. Complete dynamical analysis for a nonlinear HTLV-I infection model with distributed delay, CTL response and immune impairment. Discrete & Continuous Dynamical Systems - B, 2020, 25 (3) : 917-933. doi: 10.3934/dcdsb.2019196 [14] Eugen Stumpf. On a delay differential equation arising from a car-following model: Wavefront solutions with constant-speed and their stability. Discrete & Continuous Dynamical Systems - B, 2017, 22 (9) : 3317-3340. doi: 10.3934/dcdsb.2017139 [15] Edoardo Beretta, Dimitri Breda. Discrete or distributed delay? Effects on stability of population growth. Mathematical Biosciences & Engineering, 2016, 13 (1) : 19-41. doi: 10.3934/mbe.2016.13.19 [16] Anatoli F. Ivanov, Musa A. Mammadov. Global asymptotic stability in a class of nonlinear differential delay equations. Conference Publications, 2011, 2011 (Special) : 727-736. doi: 10.3934/proc.2011.2011.727 [17] Elena Braverman, Sergey Zhukovskiy. Absolute and delay-dependent stability of equations with a distributed delay. Discrete & Continuous Dynamical Systems, 2012, 32 (6) : 2041-2061. doi: 10.3934/dcds.2012.32.2041 [18] Cuicui Jiang, Wendi Wang. Complete classification of global dynamics of a virus model with immune responses. Discrete & Continuous Dynamical Systems - B, 2014, 19 (4) : 1087-1103. doi: 10.3934/dcdsb.2014.19.1087 [19] Alexander Rezounenko. Stability of a viral infection model with state-dependent delay, CTL and antibody immune responses. Discrete & Continuous Dynamical Systems - B, 2017, 22 (4) : 1547-1563. doi: 10.3934/dcdsb.2017074 [20] Abdelhai Elazzouzi, Aziz Ouhinou. Optimal regularity and stability analysis in the $\alpha-$Norm for a class of partial functional differential equations with infinite delay. Discrete & Continuous Dynamical Systems, 2011, 30 (1) : 115-135. doi: 10.3934/dcds.2011.30.115

2020 Impact Factor: 1.327