American Institute of Mathematical Sciences

Advanced
June  2018, 23(4): 1675-1688. doi: 10.3934/dcdsb.2018069

Boundedness and global solvability to a chemotaxis-haptotaxis model with slow and fast diffusion

Chunhua Jin ,

School of Mathematical Sciences, South China Normal University, Guangzhou, 510631, China

* Corresponding author: Chunhua Jin

Received  June 2017 Revised  August 2017 Published  January 2018

Fund Project: The author is supported by NSFC(11471127), Guangdong Natural Science Funds for Distinguished Young Scholar (2015A030306029)

In this paper, we deal with the following coupled chemotaxis-haptotaxis system modeling cancer invasionwith nonlinear diffusion,
$\left\{ \begin{array}{l}{u_t} = \Delta {u^m} - \chi \nabla \cdot \left( {u \cdot \nabla v} \right) - \xi \nabla \cdot \left( {u \cdot \nabla w} \right) + \mu u\left( {1 - u - w} \right),{\rm{in}}\;\Omega \times {{\mathbb{R}}^ + },\\{v_t} - \nabla v + v = u,\;{\rm{in}}\;\Omega \times {{\mathbb{R}}^ + },\\{w_t} = - vw,\;\;{\rm{in}}\;\Omega \times {{\mathbb{R}}^ + },\end{array} \right.$
where
$Ω\subset\mathbb R^N$
(
$N≥ 3$
) is a bounded domain. Under zero-flux boundary conditions, we showed that for any
$m>0$
, the problem admits a global bounded weak solution for any large initial datum if
$\frac{χ}{μ}$
is appropriately small. The slow diffusion case (
$m>1$
) of this problem have been studied by many authors [14,7,19,23], in which, the boundedness and the global in time solution are established for
$m>\frac{2N}{N+2}$
, but the cases
$m≤ \frac{2N}{N+2}$
remain open.
Keywords: Chemotaxis-haptotaxis, slow diffusion, fast diffusion, global weak solution, boundedness.
Mathematics Subject Classification: Primary: 92C17, 35B65; Secondary: 35M10.
Citation: Chunhua Jin. Boundedness and global solvability to a chemotaxis-haptotaxis model with slow and fast diffusion. Discrete & Continuous Dynamical Systems - B, 2018, 23 (4) : 1675-1688. doi: 10.3934/dcdsb.2018069
References:
[1]

X. Cao, Boundedness in a three-dimensional chemotaxis-haptotaxis model, Z. Angew. Math. Phys. , 67 (2016), Art. 11, 13 pp.  Google Scholar

[2]

M. A. J. Chaplain and G. Lolas, Mathematical modelling of cancer invasion of tissue: Dynamic heterogeneity, Networks and Heterogeneous Media, 1 (2006), 399-439.  doi: 10.3934/nhm.2006.1.399.  Google Scholar

[3]

T. Cieslak and C. Stinner, Finite-time blowup and global-in-time unbounded solutions to a parabolic-parabolic quasilinear Keller-Segel system in higher dimensions, J. Differential Equations, 252 (2012), 5832-5851.  doi: 10.1016/j.jde.2012.01.045.  Google Scholar

[4]

D. Horstmann and G. Wang, Blow-up in a chemotaxis model without symmetry assumptions, European J. Appl. Math., 12 (2001), 159-177.   Google Scholar

[5]

C. Jin, Boundedness and global solvability to a chemotaxis model with nonlinear diffusion, J. Differential Equations, 263 (2017), 5759-5772.  doi: 10.1016/j.jde.2017.06.034.  Google Scholar

[6]

E. Keller and A. Segel, Initiation of slime mold aggregation viewed as an instability, J. Theoret. Biol., 26 (1970), 399-415. Available from: https://www.researchgate.net/publication/17711401_Initiation_of_Slime_Mold_Aggregation_Viewed_as_an_Instability. doi: 10.1016/0022-5193(70)90092-5.  Google Scholar

[7]

Y. Li and J. Lankeit, Boundedness in a chemotaxis-haptotaxis model with nonlinear diffusion, Nonlinearity, 29 (2016), 1564-1595.  doi: 10.1088/0951-7715/29/5/1564.  Google Scholar

[8]

L. Nirenberg, On elliptic partial differential equations, Ann. Scuola Norm. Sup. Pisa, 13 (1959), 115-162.   Google Scholar

[9]

Y. Sugiyama, Time global existence and asymptotic behavior of solutions to degenerate quasilinear parabolic sys-tems of chemotaxis, Differential Integral Equations, 20 (2007), 133-180.   Google Scholar

[10]

Z. Szymanska, C. Morales-Rodrigo, M. Lachowicz and M. Chaplain, Mathematical modelling of cancer invasion of tissue: The role and effect of nonlocal interactions, Math. Models Methods Appl. Sci., 19 (2009), 257-281.  doi: 10.1142/S0218202509003425.  Google Scholar

[11]

T. Senba and T. Suzuki, Parabolic system of chemotaxis: Blowup in a finite and the infinite time, Methods Appl. Anal., 8 (2001), 349-367.  doi: 10.4310/MAA.2001.v8.n2.a9.  Google Scholar

[12]

C. Stinner, C. Surulescu and M. Winkler, Global weak solutions in a PDE-ODE system modeling multiscale cancer cell invasion, SIAM J. Math. Anal., 46 (2014), 1969-2007.  doi: 10.1137/13094058X.  Google Scholar

[13]

Y. Tao, Boundedness in a two-dimensional chemotaxis-haptotaxis system, arXiv: 1407.7382v1. Google Scholar

[14]

Y. Tao and M. Winkler, A chemotaxis-haptotaxis model: The roles of nonlinear diffusion and logistic source, SIAM J. Math. Anal., 43 (2011), 685-704.  doi: 10.1137/100802943.  Google Scholar

[15]

Y. Tao and M. Winkler, Global existence and boundedness in a Keller-Segel-Stokes model with arbitrary porous medium diffusion, Discrete Contin. Dyn. Syst., 32 (2012), 1901-1914.  doi: 10.3934/dcds.2012.32.1901.  Google Scholar

[16]

Y. Tao and M. Winkler, Large time behavior in a multidimensional chemotaxis-haptotaxis model with slow signal diffusion, SIAM J. Math. Anal., 47 (2015), 4229-4250.  doi: 10.1137/15M1014115.  Google Scholar

[17]

J. Tello and M. Winkler, A chemotaxis system with logistic source, Comm. Partial Differential Equations, 32 (2007), 849-877.  doi: 10.1080/03605300701319003.  Google Scholar

[18]

M. Winkler, Finite-time blow-up in the higher-dimensional parabolic-parabolic Keller-Segel system, J. Math. Pures Appl., 100 (2013), 748-767.  doi: 10.1016/j.matpur.2013.01.020.  Google Scholar

[19]

Y. Wang, Boundedness in the higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, J. Differential Equations, 260 (2016), 1975-1989.  doi: 10.1016/j.jde.2015.09.051.  Google Scholar

[20]

M. Winkler, Aggregation vs. global diffusive behavior in the higher-dimensional Keller-Segel model, J. Differential Equations, 248 (2010), 2889-2905.  doi: 10.1016/j.jde.2010.02.008.  Google Scholar

[21]

M. Winkler, Chemotaxis with logistic source: Very weak global solutions and their boundedness properties, J.Math. Anal. Appl., 48 (2008), 708-729.  doi: 10.1016/j.jmaa.2008.07.071.  Google Scholar

[22]

M. Winkler, Boundedness in the higher-dimensional parabolic-parabolic chemotaxis system with logistic source, Comm. Partial Differential Equations, 35 (2010), 1516-1537.  doi: 10.1080/03605300903473426.  Google Scholar

[23]

J. Zheng, Boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, Discrete Contin. Dyn. Syst., 37 (2017), 627-643.   Google Scholar

show all references

References:
[1]

X. Cao, Boundedness in a three-dimensional chemotaxis-haptotaxis model, Z. Angew. Math. Phys. , 67 (2016), Art. 11, 13 pp.  Google Scholar

[2]

M. A. J. Chaplain and G. Lolas, Mathematical modelling of cancer invasion of tissue: Dynamic heterogeneity, Networks and Heterogeneous Media, 1 (2006), 399-439.  doi: 10.3934/nhm.2006.1.399.  Google Scholar

[3]

T. Cieslak and C. Stinner, Finite-time blowup and global-in-time unbounded solutions to a parabolic-parabolic quasilinear Keller-Segel system in higher dimensions, J. Differential Equations, 252 (2012), 5832-5851.  doi: 10.1016/j.jde.2012.01.045.  Google Scholar

[4]

D. Horstmann and G. Wang, Blow-up in a chemotaxis model without symmetry assumptions, European J. Appl. Math., 12 (2001), 159-177.   Google Scholar

[5]

C. Jin, Boundedness and global solvability to a chemotaxis model with nonlinear diffusion, J. Differential Equations, 263 (2017), 5759-5772.  doi: 10.1016/j.jde.2017.06.034.  Google Scholar

[6]

E. Keller and A. Segel, Initiation of slime mold aggregation viewed as an instability, J. Theoret. Biol., 26 (1970), 399-415. Available from: https://www.researchgate.net/publication/17711401_Initiation_of_Slime_Mold_Aggregation_Viewed_as_an_Instability. doi: 10.1016/0022-5193(70)90092-5.  Google Scholar

[7]

Y. Li and J. Lankeit, Boundedness in a chemotaxis-haptotaxis model with nonlinear diffusion, Nonlinearity, 29 (2016), 1564-1595.  doi: 10.1088/0951-7715/29/5/1564.  Google Scholar

[8]

L. Nirenberg, On elliptic partial differential equations, Ann. Scuola Norm. Sup. Pisa, 13 (1959), 115-162.   Google Scholar

[9]

Y. Sugiyama, Time global existence and asymptotic behavior of solutions to degenerate quasilinear parabolic sys-tems of chemotaxis, Differential Integral Equations, 20 (2007), 133-180.   Google Scholar

[10]

Z. Szymanska, C. Morales-Rodrigo, M. Lachowicz and M. Chaplain, Mathematical modelling of cancer invasion of tissue: The role and effect of nonlocal interactions, Math. Models Methods Appl. Sci., 19 (2009), 257-281.  doi: 10.1142/S0218202509003425.  Google Scholar

[11]

T. Senba and T. Suzuki, Parabolic system of chemotaxis: Blowup in a finite and the infinite time, Methods Appl. Anal., 8 (2001), 349-367.  doi: 10.4310/MAA.2001.v8.n2.a9.  Google Scholar

[12]

C. Stinner, C. Surulescu and M. Winkler, Global weak solutions in a PDE-ODE system modeling multiscale cancer cell invasion, SIAM J. Math. Anal., 46 (2014), 1969-2007.  doi: 10.1137/13094058X.  Google Scholar

[13]

Y. Tao, Boundedness in a two-dimensional chemotaxis-haptotaxis system, arXiv: 1407.7382v1. Google Scholar

[14]

Y. Tao and M. Winkler, A chemotaxis-haptotaxis model: The roles of nonlinear diffusion and logistic source, SIAM J. Math. Anal., 43 (2011), 685-704.  doi: 10.1137/100802943.  Google Scholar

[15]

Y. Tao and M. Winkler, Global existence and boundedness in a Keller-Segel-Stokes model with arbitrary porous medium diffusion, Discrete Contin. Dyn. Syst., 32 (2012), 1901-1914.  doi: 10.3934/dcds.2012.32.1901.  Google Scholar

[16]

Y. Tao and M. Winkler, Large time behavior in a multidimensional chemotaxis-haptotaxis model with slow signal diffusion, SIAM J. Math. Anal., 47 (2015), 4229-4250.  doi: 10.1137/15M1014115.  Google Scholar

[17]

J. Tello and M. Winkler, A chemotaxis system with logistic source, Comm. Partial Differential Equations, 32 (2007), 849-877.  doi: 10.1080/03605300701319003.  Google Scholar

[18]

M. Winkler, Finite-time blow-up in the higher-dimensional parabolic-parabolic Keller-Segel system, J. Math. Pures Appl., 100 (2013), 748-767.  doi: 10.1016/j.matpur.2013.01.020.  Google Scholar

[19]

Y. Wang, Boundedness in the higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, J. Differential Equations, 260 (2016), 1975-1989.  doi: 10.1016/j.jde.2015.09.051.  Google Scholar

[20]

M. Winkler, Aggregation vs. global diffusive behavior in the higher-dimensional Keller-Segel model, J. Differential Equations, 248 (2010), 2889-2905.  doi: 10.1016/j.jde.2010.02.008.  Google Scholar

[21]

M. Winkler, Chemotaxis with logistic source: Very weak global solutions and their boundedness properties, J.Math. Anal. Appl., 48 (2008), 708-729.  doi: 10.1016/j.jmaa.2008.07.071.  Google Scholar

[22]

M. Winkler, Boundedness in the higher-dimensional parabolic-parabolic chemotaxis system with logistic source, Comm. Partial Differential Equations, 35 (2010), 1516-1537.  doi: 10.1080/03605300903473426.  Google Scholar

[23]

J. Zheng, Boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion, Discrete Contin. Dyn. Syst., 37 (2017), 627-643.   Google Scholar

[1]

Pan Zheng, Chunlai Mu, Xiaojun Song. On the boundedness and decay of solutions for a chemotaxis-haptotaxis system with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2016, 36 (3) : 1737-1757. doi: 10.3934/dcds.2016.36.1737
[2]

Pan Zheng. Global boundedness and decay for a multi-dimensional chemotaxis-haptotaxis system with nonlinear diffusion. Discrete & Continuous Dynamical Systems - B, 2016, 21 (6) : 2039-2056. doi: 10.3934/dcdsb.2016035
[3]

Ling Liu, Jiashan Zheng. Global existence and boundedness of solution of a parabolic-parabolic-ODE chemotaxis-haptotaxis model with (generalized) logistic source. Discrete & Continuous Dynamical Systems - B, 2019, 24 (7) : 3357-3377. doi: 10.3934/dcdsb.2018324
[4]

Jiashan Zheng. Boundedness of solutions to a quasilinear higher-dimensional chemotaxis-haptotaxis model with nonlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2017, 37 (1) : 627-643. doi: 10.3934/dcds.2017026
[5]

Hua Zhong, Chunlai Mu, Ke Lin. Global weak solution and boundedness in a three-dimensional competing chemotaxis. Discrete & Continuous Dynamical Systems - A, 2018, 38 (8) : 3875-3898. doi: 10.3934/dcds.2018168
[6]

Youshan Tao, Michael Winkler. A chemotaxis-haptotaxis system with haptoattractant remodeling: Boundedness enforced by mild saturation of signal production. Communications on Pure & Applied Analysis, 2019, 18 (4) : 2047-2067. doi: 10.3934/cpaa.2019092
[7]

Feng Li, Yuxiang Li. Global existence of weak solution in a chemotaxis-fluid system with nonlinear diffusion and rotational flux. Discrete & Continuous Dynamical Systems - B, 2019, 24 (10) : 5409-5436. doi: 10.3934/dcdsb.2019064
[8]

Changchun Liu, Pingping Li. Global existence for a chemotaxis-haptotaxis model with $ p $-Laplacian. Communications on Pure & Applied Analysis, 2020, 19 (3) : 1399-1419. doi: 10.3934/cpaa.2020070
[9]

Marcel Freitag. The fast signal diffusion limit in nonlinear chemotaxis systems. Discrete & Continuous Dynamical Systems - B, 2020, 25 (3) : 1109-1128. doi: 10.3934/dcdsb.2019211
[10]

Masaki Kurokiba, Toshitaka Nagai, T. Ogawa. The uniform boundedness and threshold for the global existence of the radial solution to a drift-diffusion system. Communications on Pure & Applied Analysis, 2006, 5 (1) : 97-106. doi: 10.3934/cpaa.2006.5.97
[11]

Marcel Freitag. Global existence and boundedness in a chemorepulsion system with superlinear diffusion. Discrete & Continuous Dynamical Systems - A, 2018, 38 (11) : 5943-5961. doi: 10.3934/dcds.2018258
[12]

Laiqing Meng, Jia Yuan, Xiaoxin Zheng. Global existence of almost energy solution to the two-dimensional chemotaxis-Navier-Stokes equations with partial diffusion. Discrete & Continuous Dynamical Systems - A, 2019, 39 (6) : 3413-3441. doi: 10.3934/dcds.2019141
[13]

Alexandre Caboussat, Allison Leonard. Numerical solution and fast-slow decomposition of a population of weakly coupled systems. Conference Publications, 2009, 2009 (Special) : 123-132. doi: 10.3934/proc.2009.2009.123
[14]

Zhi-An Wang, Kun Zhao. Global dynamics and diffusion limit of a one-dimensional repulsive chemotaxis model. Communications on Pure & Applied Analysis, 2013, 12 (6) : 3027-3046. doi: 10.3934/cpaa.2013.12.3027
[15]

Hongyun Peng, Lizhi Ruan, Changjiang Zhu. Convergence rates of zero diffusion limit on large amplitude solution to a conservation laws arising in chemotaxis. Kinetic & Related Models, 2012, 5 (3) : 563-581. doi: 10.3934/krm.2012.5.563
[16]

Youshan Tao, Michael Winkler. Global existence and boundedness in a Keller-Segel-Stokes model with arbitrary porous medium diffusion. Discrete & Continuous Dynamical Systems - A, 2012, 32 (5) : 1901-1914. doi: 10.3934/dcds.2012.32.1901
[17]

Shangbing Ai, Wenzhang Huang, Zhi-An Wang. Reaction, diffusion and chemotaxis in wave propagation. Discrete & Continuous Dynamical Systems - B, 2015, 20 (1) : 1-21. doi: 10.3934/dcdsb.2015.20.1
[18]

Wei Wang, Yan Li, Hao Yu. Global boundedness in higher dimensions for a fully parabolic chemotaxis system with singular sensitivity. Discrete & Continuous Dynamical Systems - B, 2017, 22 (10) : 3663-3669. doi: 10.3934/dcdsb.2017147
[19]

Johannes Lankeit, Yulan Wang. Global existence, boundedness and stabilization in a high-dimensional chemotaxis system with consumption. Discrete & Continuous Dynamical Systems - A, 2017, 37 (12) : 6099-6121. doi: 10.3934/dcds.2017262
[20]

Mengyao Ding, Wei Wang. Global boundedness in a quasilinear fully parabolic chemotaxis system with indirect signal production. Discrete & Continuous Dynamical Systems - B, 2019, 24 (9) : 4665-4684. doi: 10.3934/dcdsb.2018328

2018 Impact Factor: 1.008

Tools

Metrics

  • PDF downloads (115)
  • HTML views (465)
  • Cited by (0)

Other articles
by authors

[Back to Top]

Copyright © 2019 American Institute of Mathematical Sciences