# American Institute of Mathematical Sciences

• Previous Article
Connected components of positive solutions for a Dirichlet problem involving the mean curvature operator in Minkowski space
• DCDS-B Home
• This Issue
• Next Article
Stability of radial solutions of the Poisson-Nernst-Planck system in annular domains
June  2019, 24(6): 2683-2700. doi: 10.3934/dcdsb.2018270

## Nondegenerate multistationarity in small reaction networks

 1 Texas A&M University, Department of Mathematics, Mailstop 3368, College Station, TX 77843-3368, USA 2 Technische Universität Berlin, Institut für Mathematik, Straße des 17. Juni 136, 10623 Berlin, Germany

* Corresponding author: Anne Shiu

Received  January 2018 Revised  May 2018 Published  October 2018

Much attention has been focused in recent years on the following algebraic problem arising from applications: which chemical reaction networks, when taken with mass-action kinetics, admit multiple positive steady states? The interest behind this question is in steady states that are stable. As a step toward this difficult question, here we address the question of multiple nondegenerate positive steady states. Mathematically, this asks whether certain families of parametrized, real, sparse polynomial systems ever admit multiple positive real roots that are simple. Our main results settle this problem for certain types of small networks, and our techniques may point the way forward for larger networks.

Citation: Anne Shiu, Timo de Wolff. Nondegenerate multistationarity in small reaction networks. Discrete & Continuous Dynamical Systems - B, 2019, 24 (6) : 2683-2700. doi: 10.3934/dcdsb.2018270
##### References:

show all references

##### References:
Stoichiometric compatibility classes for the network in Example 2.2.
Summary of results on nondegenerate multistationarity for small reactions. Here r denotes the number of reactions and s the number of species. See Section 2.
 Network property Nondegenerately multistationary? Network with only 1 species ($s=1$) If and only if some subnetwork is 2-alternating (Proposition 1.1) [17] Network consists of 1 reaction ($r=1$) or 1 reversible-reaction pair No (Proposition 1.2) [17] Network consists of 2 reactions ($r=2$) See Proposition 1.3 [17] $r+s \leq 3$ No ([17,Corollary 3.8]) $s=2$ and 1 irreversible reaction and 1 reversible-reaction pair See Theorem 3.5 $s=2$ and 2 reversible-reaction pairs See Theorem 3.6
 Network property Nondegenerately multistationary? Network with only 1 species ($s=1$) If and only if some subnetwork is 2-alternating (Proposition 1.1) [17] Network consists of 1 reaction ($r=1$) or 1 reversible-reaction pair No (Proposition 1.2) [17] Network consists of 2 reactions ($r=2$) See Proposition 1.3 [17] $r+s \leq 3$ No ([17,Corollary 3.8]) $s=2$ and 1 irreversible reaction and 1 reversible-reaction pair See Theorem 3.5 $s=2$ and 2 reversible-reaction pairs See Theorem 3.6
 [1] H. M. Srivastava, H. I. Abdel-Gawad, Khaled Mohammed Saad. Oscillatory states and patterns formation in a two-cell cubic autocatalytic reaction-diffusion model subjected to the Dirichlet conditions. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020433 [2] Qiang Fu, Yanlong Zhang, Yushu Zhu, Ting Li. Network centralities, demographic disparities, and voluntary participation. Mathematical Foundations of Computing, 2020, 3 (4) : 249-262. doi: 10.3934/mfc.2020011 [3] Djamel Aaid, Amel Noui, Özen Özer. Piecewise quadratic bounding functions for finding real roots of polynomials. Numerical Algebra, Control & Optimization, 2021, 11 (1) : 63-73. doi: 10.3934/naco.2020015 [4] Shipra Singh, Aviv Gibali, Xiaolong Qin. Cooperation in traffic network problems via evolutionary split variational inequalities. Journal of Industrial & Management Optimization, 2020  doi: 10.3934/jimo.2020170 [5] Hua Chen, Yawei Wei. Multiple solutions for nonlinear cone degenerate elliptic equations. Communications on Pure & Applied Analysis, , () : -. doi: 10.3934/cpaa.2020272 [6] Youshan Tao, Michael Winkler. Critical mass for infinite-time blow-up in a haptotaxis system with nonlinear zero-order interaction. Discrete & Continuous Dynamical Systems - A, 2021, 41 (1) : 439-454. doi: 10.3934/dcds.2020216 [7] Jianquan Li, Xin Xie, Dian Zhang, Jia Li, Xiaolin Lin. Qualitative analysis of a simple tumor-immune system with time delay of tumor action. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020341 [8] Thomas Bartsch, Tian Xu. Strongly localized semiclassical states for nonlinear Dirac equations. Discrete & Continuous Dynamical Systems - A, 2021, 41 (1) : 29-60. doi: 10.3934/dcds.2020297 [9] Tommi Brander, Joonas Ilmavirta, Petteri Piiroinen, Teemu Tyni. Optimal recovery of a radiating source with multiple frequencies along one line. Inverse Problems & Imaging, 2020, 14 (6) : 967-983. doi: 10.3934/ipi.2020044 [10] Meilan Cai, Maoan Han. Limit cycle bifurcations in a class of piecewise smooth cubic systems with multiple parameters. Communications on Pure & Applied Analysis, 2021, 20 (1) : 55-75. doi: 10.3934/cpaa.2020257 [11] Stefan Ruschel, Serhiy Yanchuk. The Spectrum of delay differential equations with multiple hierarchical large delays. Discrete & Continuous Dynamical Systems - S, 2021, 14 (1) : 151-175. doi: 10.3934/dcdss.2020321 [12] D. R. Michiel Renger, Johannes Zimmer. Orthogonality of fluxes in general nonlinear reaction networks. Discrete & Continuous Dynamical Systems - S, 2021, 14 (1) : 205-217. doi: 10.3934/dcdss.2020346 [13] Scipio Cuccagna, Masaya Maeda. A survey on asymptotic stability of ground states of nonlinear Schrödinger equations II. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020450 [14] Lei Liu, Li Wu. Multiplicity of closed characteristics on $P$-symmetric compact convex hypersurfaces in $\mathbb{R}^{2n}$. Discrete & Continuous Dynamical Systems - A, 2020  doi: 10.3934/dcds.2020378 [15] Weiwei Liu, Jinliang Wang, Yuming Chen. Threshold dynamics of a delayed nonlocal reaction-diffusion cholera model. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020316 [16] Abdelghafour Atlas, Mostafa Bendahmane, Fahd Karami, Driss Meskine, Omar Oubbih. A nonlinear fractional reaction-diffusion system applied to image denoising and decomposition. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020321 [17] Serena Dipierro, Benedetta Pellacci, Enrico Valdinoci, Gianmaria Verzini. Time-fractional equations with reaction terms: Fundamental solutions and asymptotics. Discrete & Continuous Dynamical Systems - A, 2021, 41 (1) : 257-275. doi: 10.3934/dcds.2020137 [18] Noriyoshi Fukaya. Uniqueness and nondegeneracy of ground states for nonlinear Schrödinger equations with attractive inverse-power potential. Communications on Pure & Applied Analysis, 2021, 20 (1) : 121-143. doi: 10.3934/cpaa.2020260 [19] Alex H. Ardila, Mykael Cardoso. Blow-up solutions and strong instability of ground states for the inhomogeneous nonlinear Schrödinger equation. Communications on Pure & Applied Analysis, 2021, 20 (1) : 101-119. doi: 10.3934/cpaa.2020259 [20] Leilei Wei, Yinnian He. A fully discrete local discontinuous Galerkin method with the generalized numerical flux to solve the tempered fractional reaction-diffusion equation. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020319

2019 Impact Factor: 1.27