In this paper, we consider the initial-boundary value problem to the non-isothermal incompressible liquid crystal system with both variable density and temperature. Global well-posedness of strong solutions is established for initial data being small perturbation around the equilibrium state. As the tools in the proof, we establish the maximal regularities of the linear Stokes equations and parabolic equations with variable coefficients and a rigid lemma for harmonic maps on bounded domains. This paper also generalizes the result in [
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