In this paper, the following the coupled chemotaxis-haptotatxis system under zero-flux boundary conditions is studied:
$ \begin{align} \begin{cases} u_t = \Delta u-\chi\nabla\cdot\Bigg(\frac{u\nabla v}{(1+|\nabla v|^2)^\alpha}\Bigg)-\xi\nabla\cdot(u\nabla w)+\mu u(1-u-w), \, \, & x\in\Omega, \, \, t>0, \\ 0 = \Delta v-v+u, & x\in\Omega, \, \, t>0, \\ w_t = -vw, & x\in\Omega, \, \, t>0, \end{cases} \end{align} $
in a smooth and bounded domain $ \Omega\subset \mathbb{R}^n $ ($ n\ge2 $) under homogeneous Neumann boundary conditions, where $ \chi, \, \xi, \, and \mu $ are given positive parameters. For sufficiently smooth initial data ($ u_0, w_0 $), it is demonstrated that the problem possesses a unique global bounded classical solution, which is uniformly bounded in time.
| Citation: |
| [1] |
P. Biler, Existence and nonexistence of solutions for a model of gravitational interaction of particles III, Colloquium Mathematicum, 68 (1995), 229-239.
doi: 10.4064/cm-68-2-229-239.
|
| [2] |
M. A. J. Chaplain and G. Lolas, Mathematical modelling of cancer cell invasion of tissue: The role of the urokinase plasminogen activation system, Math. Models Methods Appl. Sci., 15 (2005), 1685-1734.
doi: 10.1142/S0218202505000947.
|
| [3] |
M. A. J. Chaplain and G. Lolas, Mathematical modelling of cancer invasion of tissue: Dynamic heterogeneity, Net. Hetero. Med., 1 (2006), 399-439.
doi: 10.3934/nhm.2006.1.399.
|
| [4] |
L. Corrias, B. Perthame and H. Zaag, A chemotaxis model motivated by angiogenesis, C. R. Acad. Sci. Paris, Ser. I, 336 (2003), 141-146.
|
| [5] |
L. Corrias, B. Perthame and H. Zaag, Global solutions of some chemotaxis and angiogenesis systems in high space dimensions, Milan J. Math., 72 (2004), 1-28.
doi: 10.1007/s00032-003-0026-x.
|
| [6] |
D. Gilbarg and N. S. Trudinger, Elliptic Partial Differential Equations of Second Order, New York: Springer, 1983.
|
| [7] |
M. A. Herrero and J. J. L. Velázquez, A blow-up mechanism for a chemotaxis model, Ann. Scuola Normale Superiore, 24 (1997), 633-683.
|
| [8] |
S. Hiremath and C. Surulescu, A stochastic multiscale model for acid mediated cancer invasion, Nonlinear Anal. Real World Appl., 22 (2015), 176-205.
doi: 10.1016/j.nonrwa.2014.08.008.
|
| [9] |
J. Lankeit, Eventual smoothness and asymptotics in a three-dimensional chemotaxis system with logistic source, J. Differential Equations, 258 (2015), 1158-1191.
doi: 10.1016/j.jde.2014.10.016.
|
| [10] |
G. Litcanu and C. Morales-Rodrigo, Asymptotic behaviour of global solutions to a model of cell invasion, Math. Mod. Meth. Appl. Sci., 20 (2010), 1721-1758.
doi: 10.1142/S0218202510004775.
|
| [11] |
T. Nagai, Blowup of nonradial solutions to parabolic-elliptic systems modeling chemotaxis in two-dimensional domains, J. Inequal. Appl., 6 (2001), 37-55.
|
| [12] |
T. Nagai, T. Senba and K. Yoshida, Application of the Trudinger-Moser inequality to a parabolic system of chemotaxis, Funkc. Ekvacioj, Ser. Int., 40 (1997), 411-433.
|
| [13] |
K. Osaki, T. Tsujikawa, A. Yagi and M. Mimura, Exponential attractor for a chemotaxis-growth system of equations, Nonlinear Anal. TMA, 51 (2002), 119-144.
doi: 10.1016/S0362-546X(01)00815-X.
|
| [14] |
B. Perthame, Transport Equations in Biology, Basel: Birkhäuser., 2007.
doi: 10.1007/978-3-7643-7842-4.
|
| [15] |
C. Stinner, C. Surulescu and M. Winkler, Global weak solutions in a PDE-ODE system modeling multiscale cancer cell invasion, SIAM J. Math. Anal., 46 (2014), 1969-2007.
doi: 10.1137/13094058X.
|
| [16] |
Y. Tao, Global existence for a haptotaxis model of cancer invasion with tissue remodeling, Nonlinear Anal. Real World Anal., 12 (2011), 418-435.
doi: 10.1016/j.nonrwa.2010.06.027.
|
| [17] |
Y. Tao and M. Winkler, Energy-type estimates and global solvability in a two-dimensional chemotaxis-haptotaxis model with remodeling of non-diffusible attractant, J. Differential Equations, 257 (2014), 784-815.
doi: 10.1016/j.jde.2014.04.014.
|
| [18] |
Y. Tao and M. Winkler, A chemotaxis-haptotaxis model: The roles of nonlinear diffusion and logistic source, SIAM Journal of Mathematical Analysis, 43 (2011), 685-704.
doi: 10.1137/100802943.
|
| [19] |
Y. Tao and M. Winkler, Boundedness and stabilization in a multi-dimensional chemotaxis-haptotaxis model, Proc. Roy. Soc. Edinburgh Sect. A, 144 (2014), 1067-1084.
doi: 10.1017/S0308210512000571.
|
| [20] |
Y. Tao and M. Winkler, Dominance of chemotaxis in a chemotaxis-haptotaxis model, Nonlinearity, 27 (2014), 1225-1239.
doi: 10.1088/0951-7715/27/6/1225.
|
| [21] |
C. Walker and G. F. Webb, Global existence of classical solutions for a haptotaxis model, SIAM J. Math. Anal., 38 (2007), 1694-1713.
doi: 10.1137/060655122.
|
| [22] |
M. Winkler, Aggregation versus global diffusive behavior in the higher-dimensional Keller-Segel model, J. Diff. Eqns., 248 (2010), 2889-2905.
doi: 10.1016/j.jde.2010.02.008.
|
| [23] |
M. Winkler, Finite-time blow-up in the higher-dimensional parabolic-parabolic Keller-Segel system, J. Math. Pures Appl., at press, arXiv: 1112.4156v1.
|
| [24] |
M. Winkler, Finite-time blow-up in the higher-dimensional parabolic-parabolic Keller-Segel system, Journal de Mathématiques Pures et Appliquées, 100 (2013), 748-767.
doi: 10.1016/j.matpur.2013.01.020.
|
| [25] |
M. Winkler, Boundedness in the higher-dimensional parabolic-parabolic chemotaxis system with logistic source, Comm. Partial Differential Equations, 35 (2010), 1516-1537.
doi: 10.1080/03605300903473426.
|
| [26] |
M. Winkler and K. C. Djie, Boundedness and fnite-time collapse in a chemotaxis system with volume-filling effect, Nonlinear Analysis, 72 (2010), 1044-1064.
doi: 10.1016/j.na.2009.07.045.
|