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Modelling periodic oscillations during somitogenesis

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  • We consider a model of genetic network that has been previously presented by J. Lewis. This model takes the form of delay differential equations with two delays. We give conditions for the local stability of the non-trivial steady state. We investigate the condition underwhich stability is lost and oscillations occur. In particular, we show that when the ratio of the time delays passes a threshold, sustained oscillations occur through a Hopf bifurcation. Through numerical simulations, we further investigate the ways in which various parameters influence the period and the amplitude of the oscillations. In conclusion, we discuss the implications of our results.
    Mathematics Subject Classification: Primary: 34C23, 34C25; Secondary: 92B20.

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