2009, 6(4): 839-854. doi: 10.3934/mbe.2009.6.839

Insights from epidemiological game theory into gender-specific vaccination against rubella


Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06510, United States, United States


Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA 30322, United States

Received  March 2009 Revised  June 2009 Published  September 2009

Rubella is a highly contagious childhood disease that causes relatively mild symptoms. However, rubella can result in severe congenital defects, known as congenital rubella syndrome (CRS), if transmitted from a mother to a fetus. Consequently, women have higher incentive to vaccinate against rubella than men do. Within the population vaccination reduces transmission but also increases the average age of infection and possibly the risk of CRS among unvaccinated females. To evaluate how the balance among these factors results in optimal coverage of vaccination, we developed a game theoretic age-structured epidemiological model of rubella transmission and vaccination. We found that high levels of vaccination for both genders are most effective in maximizing average utility across the population by decreasing the risk of CRS and reducing transmission of rubella. By contrast, the demands for vaccines driven by self-interest among males and females are $0\%$ and $100\%$ acceptance, respectively, if the cost of vaccination is relatively low. Our results suggest that the rubella vaccination by males that is likely to be achieved on voluntary basis without additional incentives would have been far lower than the population optimum, if rubella vaccine were offered separately instead of combined with measles and mumps vaccination as the MMR vaccine.
Citation: Eunha Shim, Beth Kochin, Alison Galvani. Insights from epidemiological game theory into gender-specific vaccination against rubella. Mathematical Biosciences & Engineering, 2009, 6 (4) : 839-854. doi: 10.3934/mbe.2009.6.839

Juan Pablo Pinasco, Mauro Rodriguez Cartabia, Nicolas Saintier. Evolutionary game theory in mixed strategies: From microscopic interactions to kinetic equations. Kinetic & Related Models, , () : -. doi: 10.3934/krm.2020051


Felix Finster, Jürg Fröhlich, Marco Oppio, Claudio F. Paganini. Causal fermion systems and the ETH approach to quantum theory. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020451


Yueyang Zheng, Jingtao Shi. A stackelberg game of backward stochastic differential equations with partial information. Mathematical Control & Related Fields, 2020  doi: 10.3934/mcrf.2020047


Pierre-Etienne Druet. A theory of generalised solutions for ideal gas mixtures with Maxwell-Stefan diffusion. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020458


Youming Guo, Tingting Li. Optimal control strategies for an online game addiction model with low and high risk exposure. Discrete & Continuous Dynamical Systems - B, 2020  doi: 10.3934/dcdsb.2020347


Claudianor O. Alves, Rodrigo C. M. Nemer, Sergio H. Monari Soares. The use of the Morse theory to estimate the number of nontrivial solutions of a nonlinear Schrödinger equation with a magnetic field. Communications on Pure & Applied Analysis, , () : -. doi: 10.3934/cpaa.2020276

2018 Impact Factor: 1.313


  • PDF downloads (53)
  • HTML views (0)
  • Cited by (23)

Other articles
by authors

[Back to Top]