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2010, 7(4): 919-922. doi: 10.3934/mbe.2010.7.919

Rotating antibiotics does not minimize selection for resistance

Sebastian Bonhoeffer 1, , Pia Abel zur Wiesch 1, and  Roger D. Kouyos 1,

1. 

Institute of Integrative Biology, ETH Zürich, CH-8092 Zurich, Switzerland, Switzerland, Switzerland

Received  August 2010 Revised  September 2010 Published  October 2010

N/A
Keywords: antibiotics, drug resistance, cycling, Epidemiology, mixing..
Mathematics Subject Classification: 92B05, 92C50, 92D30, 93C1.
Citation: Sebastian Bonhoeffer, Pia Abel zur Wiesch, Roger D. Kouyos. Rotating antibiotics does not minimize selection for resistance. Mathematical Biosciences & Engineering, 2010, 7 (4) : 919-922. doi: 10.3934/mbe.2010.7.919
References:
[1]

R. Beardmore and R. Peñal-Miller, Rotating antibiotics selects optimally against antibiotic resistance,, Mathematical Biosciences and Engineering, 7 (2010), 527.  doi: doi:10.3934/mbe.2010.7.527.  Google Scholar

[2]

S. Bonhoeffer, M. Lipsitch and B. R. Levin, Evaluating treatment protocols to prevent antibiotic resistance,, PNAS, 94 (1997), 12106.  doi: doi:10.1073/pnas.94.22.12106.  Google Scholar

[3]

C. T. Bergstrom, M. Lo and M. Lipsitch, Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals,, PNAS, 101 (2004), 13285.  doi: doi:10.1073/pnas.0402298101.  Google Scholar

show all references

References:
[1]

R. Beardmore and R. Peñal-Miller, Rotating antibiotics selects optimally against antibiotic resistance,, Mathematical Biosciences and Engineering, 7 (2010), 527.  doi: doi:10.3934/mbe.2010.7.527.  Google Scholar

[2]

S. Bonhoeffer, M. Lipsitch and B. R. Levin, Evaluating treatment protocols to prevent antibiotic resistance,, PNAS, 94 (1997), 12106.  doi: doi:10.1073/pnas.94.22.12106.  Google Scholar

[3]

C. T. Bergstrom, M. Lo and M. Lipsitch, Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals,, PNAS, 101 (2004), 13285.  doi: doi:10.1073/pnas.0402298101.  Google Scholar

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