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Antibiotic cycling versus mixing: The difficulty of using mathematical models to definitively quantify their relative merits
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An elementary approach to modeling drug resistance in cancer
Rotating antibiotics does not minimize selection for resistance
| 1. | Institute of Integrative Biology, ETH Zürich, CH-8092 Zurich, Switzerland, Switzerland, Switzerland |
References:
| [1] |
R. Beardmore and R. Peñal-Miller, Rotating antibiotics selects optimally against antibiotic resistance, Mathematical Biosciences and Engineering, 7 (2010), 527-552.
doi: doi:10.3934/mbe.2010.7.527. |
| [2] |
S. Bonhoeffer, M. Lipsitch and B. R. Levin, Evaluating treatment protocols to prevent antibiotic resistance, PNAS, 94 (1997), 12106-12111.
doi: doi:10.1073/pnas.94.22.12106. |
| [3] |
C. T. Bergstrom, M. Lo and M. Lipsitch, Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals, PNAS, 101 (2004), 13285-13290.
doi: doi:10.1073/pnas.0402298101. |
show all references
References:
| [1] |
R. Beardmore and R. Peñal-Miller, Rotating antibiotics selects optimally against antibiotic resistance, Mathematical Biosciences and Engineering, 7 (2010), 527-552.
doi: doi:10.3934/mbe.2010.7.527. |
| [2] |
S. Bonhoeffer, M. Lipsitch and B. R. Levin, Evaluating treatment protocols to prevent antibiotic resistance, PNAS, 94 (1997), 12106-12111.
doi: doi:10.1073/pnas.94.22.12106. |
| [3] |
C. T. Bergstrom, M. Lo and M. Lipsitch, Ecological theory suggests that antimicrobial cycling will not reduce antimicrobial resistance in hospitals, PNAS, 101 (2004), 13285-13290.
doi: doi:10.1073/pnas.0402298101. |
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