# American Institute of Mathematical Sciences

2012, 9(1): 61-74. doi: 10.3934/mbe.2012.9.61

## An evaluation of dynamic outlet boundary conditions in a 1D fluid dynamics model

 1 Department of Biomedical Engineering, North Carolina State University, Raleigh, NC 27695-7115, United States 2 Department of Biomedical Engineering, Engineering Building 3, RM 4204B, North Carolina State University, Raleigh, NC 27695-7115, United States

Received  February 2011 Revised  August 2011 Published  December 2011

When modeling the cardiovascular system, the use of boundary conditions that closely represent the interaction between the region of interest and the surrounding vessels and organs will result in more accurate predictions. An often overlooked feature of outlet boundary conditions is the dynamics associated with regulation of the distribution of pressure and flow. This study implements a dynamic impedance outlet boundary condition in a one-dimensional fluid dynamics model using the pulmonary vasculature and respiration (feedback mechanism) as an example of a dynamic system. The dynamic boundary condition was successfully implemented and the pressure and flow were predicted for an entire respiration cycle. The cardiac cycles at maximal expiration and inspiration were predicted with a root mean square error of $0.61$ and $0.59$ mm Hg, respectively.
Citation: Rachel Clipp, Brooke Steele. An evaluation of dynamic outlet boundary conditions in a 1D fluid dynamics model. Mathematical Biosciences & Engineering, 2012, 9 (1) : 61-74. doi: 10.3934/mbe.2012.9.61
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