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An extension of Gompertzian growth dynamics: Weibull and Fréchet models

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  • In this work a new probabilistic and dynamical approach to an extension of the Gompertz law is proposed. A generalized family of probability density functions, designated by $Beta^*(p,q)$, which is proportional to the right hand side of the Tsoularis-Wallace model, is studied. In particular, for $p = 2$, the investigation is extended to the extreme value models of Weibull and Fréchet type. These models, described by differential equations, are proportional to the hyper-Gompertz growth model. It is proved that the $Beta^*(2,q)$ densities are a power of betas mixture, and that its dynamics are determined by a non-linear coupling of probabilities. The dynamical analysis is performed using techniques of symbolic dynamics and the system complexity is measured using topological entropy. Generally, the natural history of a malignant tumour is reflected through bifurcation diagrams, in which are identified regions of regression, stability, bifurcation, chaos and terminus.
    Mathematics Subject Classification: Primary: 92D25, 91B62, 62H10, 11S82; Secondary: 92B05, 37H20, 37B10, 37B40.

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