American Institute of Mathematical Sciences

• Previous Article
Threshold dynamics of a periodic SIR model with delay in an infected compartment
• MBE Home
• This Issue
• Next Article
Global stability of a multiple delayed viral infection model with general incidence rate and an application to HIV infection
2015, 12(3): 537-554. doi: 10.3934/mbe.2015.12.537

Cell scale modeling of electropermeabilization by periodic pulses

 1 Inria Bordeaux Sud-Ouest, 200, Rue de la Veille Tour, 33405 Talence, France

Received  November 2013 Revised  January 2015 Published  January 2015

In this paper, we focus on the behaviour of periodic solutions to a cell-scale electropermeabilization model previously proposed by Kavian et al. [6]. Since clinical permeabilization protocols mostly submit cancer cells to trains of periodic pulses, we investigate on parameters that modify significantly the resulting permeabilization. Theoretical results of existence and uniqueness of periodic solutions are presented, for two different models of membrane electric conductivity. Numerical simulations were performed to corroborate these results and illustrate the asymptotic convergence to periodic solutions, as well as the dependency on biological parameters such as the cell size and the extracellular conductivity.
Citation: Michael Leguèbe. Cell scale modeling of electropermeabilization by periodic pulses. Mathematical Biosciences & Engineering, 2015, 12 (3) : 537-554. doi: 10.3934/mbe.2015.12.537
References:

show all references

References:
 [1] Denis Serre. Non-linear electromagnetism and special relativity. Discrete & Continuous Dynamical Systems - A, 2009, 23 (1&2) : 435-454. doi: 10.3934/dcds.2009.23.435 [2] Noufel Frikha, Valentin Konakov, Stéphane Menozzi. Well-posedness of some non-linear stable driven SDEs. Discrete & Continuous Dynamical Systems - A, 2021, 41 (2) : 849-898. doi: 10.3934/dcds.2020302 [3] Lorenzo Zambotti. A brief and personal history of stochastic partial differential equations. Discrete & Continuous Dynamical Systems - A, 2021, 41 (1) : 471-487. doi: 10.3934/dcds.2020264 [4] Ahmad El Hajj, Hassan Ibrahim, Vivian Rizik. $BV$ solution for a non-linear Hamilton-Jacobi system. Discrete & Continuous Dynamical Systems - A, 2020  doi: 10.3934/dcds.2020405 [5] Yueyang Zheng, Jingtao Shi. A stackelberg game of backward stochastic differential equations with partial information. Mathematical Control & Related Fields, 2020  doi: 10.3934/mcrf.2020047 [6] Hua Qiu, Zheng-An Yao. The regularized Boussinesq equations with partial dissipations in dimension two. Electronic Research Archive, 2020, 28 (4) : 1375-1393. doi: 10.3934/era.2020073 [7] Alain Bensoussan, Xinwei Feng, Jianhui Huang. Linear-quadratic-Gaussian mean-field-game with partial observation and common noise. Mathematical Control & Related Fields, 2021, 11 (1) : 23-46. doi: 10.3934/mcrf.2020025 [8] Fabio Camilli, Giulia Cavagnari, Raul De Maio, Benedetto Piccoli. Superposition principle and schemes for measure differential equations. Kinetic & Related Models, 2021, 14 (1) : 89-113. doi: 10.3934/krm.2020050 [9] Liang Huang, Jiao Chen. The boundedness of multi-linear and multi-parameter pseudo-differential operators. Communications on Pure & Applied Analysis, , () : -. doi: 10.3934/cpaa.2020291 [10] Stefan Ruschel, Serhiy Yanchuk. The spectrum of delay differential equations with multiple hierarchical large delays. Discrete & Continuous Dynamical Systems - S, 2021, 14 (1) : 151-175. doi: 10.3934/dcdss.2020321 [11] John Mallet-Paret, Roger D. Nussbaum. Asymptotic homogenization for delay-differential equations and a question of analyticity. Discrete & Continuous Dynamical Systems - A, 2020, 40 (6) : 3789-3812. doi: 10.3934/dcds.2020044 [12] Mugen Huang, Moxun Tang, Jianshe Yu, Bo Zheng. A stage structured model of delay differential equations for Aedes mosquito population suppression. Discrete & Continuous Dynamical Systems - A, 2020, 40 (6) : 3467-3484. doi: 10.3934/dcds.2020042 [13] Bixiang Wang. Mean-square random invariant manifolds for stochastic differential equations. Discrete & Continuous Dynamical Systems - A, 2021, 41 (3) : 1449-1468. doi: 10.3934/dcds.2020324 [14] Rim Bourguiba, Rosana Rodríguez-López. Existence results for fractional differential equations in presence of upper and lower solutions. Discrete & Continuous Dynamical Systems - B, 2021, 26 (3) : 1723-1747. doi: 10.3934/dcdsb.2020180 [15] Thabet Abdeljawad, Mohammad Esmael Samei. Applying quantum calculus for the existence of solution of $q$-integro-differential equations with three criteria. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020440 [16] Fathalla A. Rihan, Hebatallah J. Alsakaji. Stochastic delay differential equations of three-species prey-predator system with cooperation among prey species. Discrete & Continuous Dynamical Systems - S, 2020  doi: 10.3934/dcdss.2020468 [17] Guangjun Shen, Xueying Wu, Xiuwei Yin. Stabilization of stochastic differential equations driven by G-Lévy process with discrete-time feedback control. Discrete & Continuous Dynamical Systems - B, 2021, 26 (2) : 755-774. doi: 10.3934/dcdsb.2020133 [18] Tin Phan, Bruce Pell, Amy E. Kendig, Elizabeth T. Borer, Yang Kuang. Rich dynamics of a simple delay host-pathogen model of cell-to-cell infection for plant virus. Discrete & Continuous Dynamical Systems - B, 2021, 26 (1) : 515-539. doi: 10.3934/dcdsb.2020261 [19] Andy Hammerlindl, Jana Rodriguez Hertz, Raúl Ures. Ergodicity and partial hyperbolicity on Seifert manifolds. Journal of Modern Dynamics, 2020, 0: 331-348. doi: 10.3934/jmd.2020012 [20] Jonathan J. Wylie, Robert M. Miura, Huaxiong Huang. Systems of coupled diffusion equations with degenerate nonlinear source terms: Linear stability and traveling waves. Discrete & Continuous Dynamical Systems - A, 2009, 23 (1&2) : 561-569. doi: 10.3934/dcds.2009.23.561

2018 Impact Factor: 1.313