Viable flux distribution in metabolic networks

Ginestra Bianconi; Riccardo Zecchina

doi:10.3934/nhm.2008.3.361

Article Contents

2008, Volume 3, Issue 2: 361-369. Doi: 10.3934/nhm.2008.3.361

This issue Previous Article On the relationships between topological measures in real-world networks Next Article K-core decomposition of Internet graphs: hierarchies, self-similarity and measurement biases

Viable flux distribution in metabolic networks

Ginestra Bianconi^1, and
Riccardo Zecchina^2,

1.
The Abdus Salam ICTP, Strada Costiera 11, 34014 Trieste
2.
Politecnico di Torino, Corso Duca degli Abruzzi, 34, I-10129, Torino

Received: September 2007

Revised: February 2008

Published: June 2008

Abstract / Introduction Related Papers Cited by

Abstract

The metabolic networks are very well characterized for bacterial such of E.coli. For this reason they provide a a very interesting framework for the construction of analytically tractable statistical mechanics models. In this paper we introduce a solvable model for the distribution of fluxes in the metabolic network. We show that the effect of the topology on the distribution of fluxes is to allow for large fluctuations of their values, a fact that should have implications on the robustness of the system.

Keywords:

Mathematics Subject Classification: Primary: 58F15, 58F17; Secondary: 53C35.

Citation:

Article Metrics

HTML views() PDF downloads(53) Cited by(0)

Viable flux distribution in metabolic networks

Abstract

Access History

Article Metrics

Access History

Other Articles By Authors

Catalog

Viable flux distribution in metabolic networks

Abstract

Access History

SHARE

Article Metrics

Access History

Other Articles By Authors

Catalog

Export File

Citation

Format

Content