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Dynamics of microfluidic mixing using time pulsing

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  • Many microfluidic applications require the mixing of reagents, but efficient mixing in these laminar systems remains a challenge. In this paper, we consider further the method of pulsed flow mixing which takes advantage of time dependency rather than spatial complexity. In particular, using computational fluid dynamics (CFD) we analyze the dynamics of the flow when the two inlets are pulsed at $90^\circ$ and $180^\circ$ out of phase. Both cases achieve enhanced mixing although better results occur in the first case. This is apparent in the concentration level plots as well as in the shape of material lines which show strong repeated stretching and folding at the confluence region.
    Mathematics Subject Classification: Primary:58F15, 58F17; Secondary: 53C35.


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